Dear Rob Weeder,
The error message is saying "Access denied". Can you find the image upload folder, give everyone full control and see what happens?
If problem persists, can find our online demo inside download package CS/VB folder. Uploade one of the demos ie localization.aspx to their website and see if it makes any difference.
If still not working, we will need to login to the customer site together and debug. In that case, please come to LiveSupport at
http://CuteSoft.net, click on the big blue button on top that reads "online". We are here Monday - Friday between 9:30am and 17:30pm Eastern Standard Time.
Thanks for using our product