Hello guys,  

Feel free to pay me $100 for this fix if you like :-)

I think that the Update Panel isn't rendering the Javascript up through the update panel because of the weird way that the CuteSoft Editor is loading the JavaScript. Doesn't matter though, just reference the NetSpell SpellCheck JavaScript file directly at the top of each page in the Head section that uses the CuteSoft Editor inside an update panel.

<script language="javascript" type="text/javascript" src="cutesoft_Client/CuteEditor/Load.ashx?type=script&file=spell.js">
</script>

Thanks,