*.resx files are temp files which will be removed by Ajax Uploader automatically.
Unlike standard ASP.NET HtmlInputFile control, AJAX Uploader does not read the entire uploaded file into memory. It streams the data into a temporary file while the data is received. For this reason, you must specify a temporary file location. You should ensure that the ASPNET user (NetworkService in Windows Server 2003) has read/write permission to this specified folder.
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