Scott,
>>To set up Live Support so that can clients can contact support from any of the domains, I presume that I would need to create virtual directories for each domain that point to one set of Live Support files. Are there other issues?
It will work. Just make sure you need to modify SupportHome.aspx to handle different domains.
SupportHome.aspx is the default aspx page that is loaded into HOME tab of operator client.
asp.net Chat http://cutesoft.net/ASP.NET+Chat/default.aspx
Web Messenger: http://cutesoft.net/Web-Messenger/default.aspx
asp.net wysiwyg editor: http://cutesoft.net/ASP.NET+WYSIWYG+Editor/default.aspx
asp wysiwyg html editor: http://cutesoft.net/ASP
asp.net Image Gallery: http://cutesoft.net/ASP.NET+Image+Gallery/default.aspx
Live Support: http://cutesoft.net/live-support/default.aspx