Ben,
>>Apart from the Temp folder (or the one listed in CuteEditorTempPath setting), does it need access to another folder?
No.
Please check your .net framework version as well. If you are using .net framework 2.0, please use the CuteEditor.dll for .net 2.0.
I also suggest you upgrade your version 5.2 to the latest build of version 5.3.
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